Kathleen Murphy, M.D. is a board-certified pediatric intensivist with a passion for clinical
research, medical education and public health policy. In 2005, she voluntarily opened a study
site for a multi-center phase III trial for children with severe sepsis at Valley Children’s Hospital,
Madera CA. The study, Drotrecogin alfa (activated) in children with severe sepsis: a multicentre
phase III randomised controlled trial, was the first randomised, placebo controlled trial
conducted in the PICU at Valley Children’s Hospital. The PICU subsequently joined a national
clinical research network, PALISI (Pediatric Acute Lung Injury and Sepsis Investigators) to
carryout multiple arms of multi center clinical studies. She further worked to develop, validate,
and implement a pediatric trigger tool to detect adverse events in hospitalized pediatric patients
over a five year period. The volunteer multidisciplinary team ultimately joined teams at five other
children’s hospitals to collaborate on testing an automated trigger tool (Pediatric All-Cause Harm
Measurement Tool) anticipating integration into electronic medical records which would enable
real-time detection and hence possible prevention of patient harm.
During her time at Valley Children’s, Dr. Murphy also developed and administered a physician
shadow and mentor program in the ICU to encourage promising high school students interested
in science and health care to pursue those fields. The program involved shadowing a physician
for several weeks during school breaks and participating in all non-patient-contact aspects of
critical care. Notably, four participants of this program have matriculated to either medical
school or PhD programs, including a Fullbright scholar now studying viral reservoirs in bats.
Dr. Murphy serves as chief health care policy advisor for the TJ Cox for Congress campaign.
She has also contributed her time and efforts to a number of professional and non-profit boards
including her medical group, Pediatric Anesthesia Associates Medical Group, as well as other
school and youth sports club boards.